Adenyl cyclase activities in rat erythrocytes during stress erythropoiesis: localization of the enzyme in the reticulocytes |
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| Authors: | D Gauger D Palm G Kaiser K Quiring |
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| Institution: | Pharmakologisches Institut der Universität, 6000 Frankfurt 70, West Germany |
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| Abstract: | NaF- and isoproterenol-stimulated adenyl cyclase activity found in preparations from rat erythrocytes is obviously localized mainly in the reticulocytes. After treatment with acetylphenyl hydrazine, both reticulocyte counts and adenyl cyclase activity increase dose-dependently. Evidence is given that adenyl cyclase activity in the red blood cell is lost during the maturation process. |
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