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Degeneracy of the genetic code and stability of the base pair at the second position of the anticodon
Authors:Lehmann Jean  Libchaber Albert
Affiliation:Center for Studies in Physics and Biology, The Rockefeller University, New York, New York 10065, USA
Abstract:With an analysis of the structural constraints of the anticodon-codon interaction within the decoding center of the ribosome, we show that the extent of degeneracy at the third position of the anticodon is determined by the level of stability of the base pair at the second position.
Keywords:tRNA   anticodon loop   U-turn   decoding center   wobble   degeneracy
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