University of Hohenheim, Institute of Zoology, Garbenstrasse 30, 70593 Stuttgart, Germany.
Abstract:
Highlights? ATP4 is required during gastrulation/neurulation for cilia-driven leftward flow to occur ? ATP4 acts on canonical and noncanonical Wnt signaling ? Wnt/β-catenin is necessary and sufficient for gastrula Foxj1 expression ? Leftward flow is the conserved mode of symmetry breakage in Xenopus