Sex hormone drives blood stem cell reproduction |
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| Authors: | Vincenzo Calvanese Lydia K Lee Hanna K A Mikkola |
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| Institution: | 1. Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA;2. Department of Obstetrics and Gynecology, University of California Los Angeles, Los Angeles, CA, USA;3. Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA |
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| Abstract: | Stem cells ensure the maintenance of tissue homeostasis throughout life by tightly regulating their self‐renewal and differentiation. In a recent study published in Nature, Nakada et al, 2014 unveil an unexpected endocrine mechanism that regulates hematopoietic stem cell (HSC) self‐renewal. |
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