Studies on cystathionase activity in rat liver and brain during development. Effects of hormones and amino acids in vivo |
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| Authors: | Kirsti Heinonen |
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| Institution: | Children''s Hospital, University of Helsinki, Stenbäck Street 11, Helsinki 29, Finland, and Department of Medical Chemistry, University of Helsinki, Siltavuorenpenger 10, Helsinki 17, Finland |
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| Abstract: | High activity of cystathionase was present in rat liver but only low amounts of activity in rat brain during development. Triamcinolone had no effect on liver cystathionase activity in foetuses but increased the enzyme activity significantly in postnatal rats. l-Thyroxine decreased liver cystathionase activity significantly in newborn rats; administration of pyridoxal 5'-phosphate did not prevent this effect. l-Methionine significantly increased liver cystathionase activity in newborn rats. |
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