(1) Department of Medical Microbiology, Barts and the London, Queen Mary's School of Medicine and Dentistry, London, UK;(2) Department of Infectious & Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK
Abstract:
Background
The acetamidase of Mycobacterium smegmatis is a highly inducible enzyme. Expression of this enzyme is increased 100-fold when the substrate acetamide is present. The acetamidase gene is found immediately downstream of three open reading frames. Two of these are proposed to be involved in regulation.