Tricyclic antidepressants, quinacrine and a novel, synthetic chimera thereof clear prions by destabilizing detergent-resistant membrane compartments |
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Authors: | Ralf Klingenstein,Stefan Lö ber&dagger ,Pekka Kujala&Dagger ,Susan Godsave&Dagger ,S. Rutger Leliveld,Peter Gmeiner&dagger ,Peter J. Peters&Dagger , Carsten Korth |
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Affiliation: | Institute for Neuropathology, Heinrich Heine University of Düsseldorf, Düsseldorf, Germany; Institute for Pharmaceutical Chemistry, Friedrich-Alexander University Erlangen-Nu¨rnberg, Erlangen, Germany; Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, the Netherlands |
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