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Over-accumulation of nuclear IGF-1 receptor in tumor cells requires elevated expression of the receptor and the SUMO-conjugating enzyme Ubc9
Authors:Deng Hua  Lin Yingbo  Badin Margherita  Vasilcanu Daiana  Strömberg Thomas  Jernberg-Wiklund Helena  Sehat Bita  Larsson Olle
Institution:aDepartment of Oncology and Pathology, The Karolinska Institute, Cancer Center Karolinska, SE-17176 Stockholm, Sweden;bDepartment of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden
Abstract:
Keywords:IGF-1 receptor  Nuclear  Cell nucleus  SUMOylation  Ubc9
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