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| 内生链霉菌Streptomyces sp.Ly221的次生代谢成分 | |
| 引用本文： | 魏国柱,王浩鑫,李刚,沈月毛,赵沛基.内生链霉菌Streptomyces sp.Ly221的次生代谢成分[J].天然产物研究与开发,2009,21(5):727-730. |
| 作者姓名： | 魏国柱 王浩鑫 李刚 沈月毛 赵沛基 |
| 作者单位： | 1. 中国科学院昆明植物研究所,植物化学与西部植物资源持续利用国家重点实验室,昆明,650204;中国科学院研究生院,北京,100039 2. 云南中医学院,昆明,650011 3. 中国科学院昆明植物研究所,植物化学与西部植物资源持续利用国家重点实验室,昆明,650204 |
| 摘 要： | 从云南美登木茎皮组织分离得到内生菌Ly221，经16SrDNA部分核酸序列鉴定该菌属于链霉菌属（Streptomyces）。从其液体发酵提取物中分离得到5个化合物，经波谱分析鉴定其结构分别为：4，10-dihydroxy-10-methyl-dodee-2-en-1，4-olide（1）、两个非对映异构体4，11-dihydroxy-10-methyldodec-2-ell-1，4-olides（2／3）、4-hy-droxy-10-methyl-11-oxo-dodec-2-ell-1，4-olide（4）和N—aeetyltyramine（5）。 |
| 关 键 词： | 内生菌 云南美登木 烯丁酸内酯 |
Metabolites from Endophytic Streptomyces sp. Ly221 |
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| WEI Guo-zhu,WANG Hao-xin,LI Gang,SHEN Yue-mao,ZHAO Pei-ji.Metabolites from Endophytic Streptomyces sp. Ly221[J].Natural Product Research and Development,2009,21(5):727-730. | |
| Authors: | WEI Guo-zhu WANG Hao-xin LI Gang SHEN Yue-mao ZHAO Pei-ji |
| Abstract: | The strain Ly221 was isolated from the branch tissue of Maytenus hookeri and determined to be a member of Streptomyces according to the 16S rDNA sequence. The extracts from the fermentation broth of Streptomyces sp. Ly221 were purified,and five compounds were obtained. They were identified to be 4,10-dihydroxy-10-methyl-dodec-2-en-l ,4-olide (1) , two diastereomeric 4,11 -dihydroxy-10-methyldodec-2-en-1, 4-olides (2/3 ) , 4-hydroxy-10-methyl-l 1-oxo-do-dec-2-en-1 ,4-olide(4) and N-acetyltyramine(5) based on spectral data,respectively. |
| Keywords: | endophytes Maytenus hookeri butenolides |
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