Resolution of apparent growth hormone-dependent growth failure during puberty: a case report |
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Authors: | A J Weissberger K Y Ho L Lazarus |
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Institution: | Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, Australia. |
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Abstract: | A prepubertal boy with apparent growth hormone (GH)-dependent growth failure displayed a marked increase in growth velocity, normal GH responses to arginine/insulin infusion and a fourfold increase in spontaneous 24-hour GH secretion following the onset of normal puberty. The case supports earlier observations of a transient form of GH insufficiency in some short prepubertal children, but represents the first evidence that puberty restores spontaneous as well as stimulated GH secretion in such patients. |
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