| 抗菌药物用量与耐药相关分析 |
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| 引用本文： | 石娜,徐卫,舒雪芹,薛利霞,廖洪菊,张群瑜.抗菌药物用量与耐药相关分析[J].中国微生态学杂志,2007,19(5):463-464. |
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| 作者姓名： | 石娜 徐卫 舒雪芹 薛利霞 廖洪菊 张群瑜 |
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| 作者单位： | 温州医学院附属第一医院,浙江,温州,325000 |
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| 摘 要： | 目的研究抗菌药物用量与耐药的关系。方法对1998年至2002年我院住院病人抗菌药物的用量与医院感染主要病原菌的耐药进行相关分析。结果头孢噻肟的用量与大肠埃希菌对头孢噻肟的耐药率呈显著正相关(r=0.911,P=0.032);亚胺培南/西司他丁的用量与铜绿假单胞菌对亚胺培南的耐药率呈显著正相关(r=0.996,P=0.004)。结论加强抗菌药物的合理使用有助于改善当前微生物敏感性降低的形势。
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| 关 键 词： | 抗菌药物用量 耐药 相关 |
| 文章编号： | 1005-376X（2007）05-0463-02 |
| 收稿时间： | 2005-11-16 |
| 修稿时间： | 2005-11-16 |
A correlation analysis on antimicrobial usage and resistance |
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| SHI Na,XU Wei,SHU Xue-qin,XUE Li-xia,LIAO Hong-ju,ZHANG Qun-yu.A correlation analysis on antimicrobial usage and resistance[J].Chinese Journal of Microecology,2007,19(5):463-464. |
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| Authors: | SHI Na XU Wei SHU Xue-qin XUE Li-xia LIAO Hong-ju ZHANG Qun-yu |
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| Institution: | The First A ffiated Hospital, Wenzhou Medical College, Wenzhou 325000, China |
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| Abstract: | Objective To investigate the relationship between antimicrobial usage and resistance.Method A correlation analysis on antimicrobial usage for inpatients and antimicrobial resistance of prominent nosocomial pathogens between 1998~2002.Results A significant strong positive correlation was observed between the usage of cefotaxime and the prevalence of cefotaxime resistant Escherichia coli(r=0.911,P=0.032)and the usage of imipenem/cilastation and the prevalence of imipenem resistant Pseudomonas aeruginosa(r=0.996,P=0.004).Conclusion It indicated that strengthening the rational use of antimicrobial could improve the current situation of reduced microbial susceptibility. |
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| Keywords: | Antimicrobial usage Resistance Correlation |
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