Biochemical studies of toxic agents. The metabolism of iodomethane |
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| Authors: | E A Barnsley and L Young |
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| Institution: | Department of Biochemistry, St Thomas''s Hospital Medical School, London, S.E. 1 |
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| Abstract: | 1. The metabolism of iodomethane has been studied after the administration of the compound to rats by subcutaneous injection. 2. The urinary excretion of S-methylcysteine, methylmercapturic acid, methylthioacetic acid and N-(methylthioacetyl)glycine has been demonstrated by paper chromatography. 3. Methylmercapturic acid and N-(methylthioacetyl)glycine have been isolated from the urine of the dosed animals. 4. The methylthio compounds detected represented about 2% of the iodomethane administered. |
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