Isolation of Orientia tsutsugamushi from patients in Shikoku and finding of a strain which grows preferentially at low temperatures |
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Authors: | Tamura A Makisaka Y Enatsu T Urakami H Okubo K Fukuhara M Mahara F |
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Institution: | Niigata College of Pharmacy, Department of Microbiology, Niigata, Japan. tamura@niigata-pharm.ac.jp |
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Abstract: | Three strains of Orientia tsutsugamushi were isolated from patients in Anan City, Tokushima Prefecture. The strains were identified as Karp type by analyses of reactivities with type-specific monoclonal antibodies. One strain, Okazaki, was isolated in L cells cultivated at 31 C, but not in cells at 36 C or in mice. This strain showed better growth at 31 C than 36 C. This is the first report of an O. tsutsugamushi strain which grows preferentially at low temperatures. |
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Keywords: | orientia tsutsugamushi isolation temperature-sensitive strain |
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