| L－赖氨酸快速发酵新菌种及工艺研究 |
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| 引用本文： | 王磊,李宗林,沈洁,任大明,陈飞,王永泰. L－赖氨酸快速发酵新菌种及工艺研究[J]. 氨基酸和生物资源, 1995, 0(3) |
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| 作者姓名： | 王磊 李宗林 沈洁 任大明 陈飞 王永泰 |
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| 作者单位： | 复旦大学遗传学研究所，上海天厨味精厂 |
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| 摘 要： | 以我室选育的赖氨酸生产菌Ｓ－２１－２４为出发菌株，经硫酸二乙酯（ＤＥＳ）和紫外线（Ｕ．Ｖ．）的复合处理，选育到一株代谢速率高，发酵周期短的新菌株ＦＴＳ－１。对该菌的发酵条件作了研究，选择了最佳培养条件，该菌在５Ｌ发酵罐中发酵４８小时产酸８０ｇ／Ｌ以上，７２小时产酸可达１１０ｇ／Ｌ。
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| 关 键 词： | L－赖氨酸，诱变，发酵 |
Studies on the Selection and Fermentation Conditions of L-Lysine-Producing Strain |
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| Wang Lei,Li Zonglin, Shen Jie,Ren Daming. Studies on the Selection and Fermentation Conditions of L-Lysine-Producing Strain[J]. Amino Acids & Biotic Resources, 1995, 0(3) |
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| Authors: | Wang Lei Li Zonglin Shen Jie Ren Daming |
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| Abstract: | In this paper the L-Lysine producer of Corynebacterium glutamicum S-21-24 has been improved. After mutagenesis by DES and U.V.,a higher L-Lysine-Producing strain FTS-1 has been obtained. It is faster in metabolic rate and shorter in fermentation period than strain s-21-24. In the meanwhile the fermentation technology has been investigated. Under the optimal conditions, FTS-1 can accmulate 80g/lL and 110g/lL Lys-HCl after 48hr and 72 hr respectively in 5L fermentor. |
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| Keywords: | L-Lysine Mutagenesis Fermentation |
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