Chemical and enzymatic synthesis and antiviral properties of 2'-deoxy-2'-fluoroguanosine. |
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| Authors: | G V Zaitseva A I Zinchenko V N Barai N I Pavlova E I Boreko I A Mikhailopulo |
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| Institution: | Institute of Bioorganic Chemistry, National Academy of Sciences, Belarus. |
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| Abstract: | Chemical and enzymatic methods were employed for the synthesis of the title compound, 2'F-Guo 7. High antiviral activity of 2'F-Guo was established in chick embryo cells infected with influenza virus FPV/Rostock/34 (H7N1) and herpes simplex virus (HSV) type I (1C strain). |
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