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Aspirin Recapitulates Features of Caloric Restriction
Authors:Federico Pietrocola  Francesca Castoldi  Maria Markaki  Sylvie Lachkar  Guo Chen  David P. Enot  Sylvere Durand  Noelie Bossut  Mingming Tong  Shoaib A. Malik  Friedemann Loos  Nicolas Dupont  Guillermo Mariño  Nejma Abdelkader  Frank Madeo  Maria Chiara Maiuri  Romano Kroemer  Patrice Codogno  Guido Kroemer
Affiliation:1. Gustave Roussy Cancer Campus, Villejuif, France;2. INSERM, U1138, Paris, France;3. Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France;4. Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France;5. Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France;6. Université Pierre et Marie Curie, Paris, France;7. Université Paris-Sud/Paris XI, Faculté de Médecine, Kremlin-Bicêtre, France, Paris, France;8. Sotio a.c., Prague, Czech Republic;9. Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Heraklion 70013, Crete, Greece;10. Department of Cell Biology and Molecular Medicine, Rutgers–New Jersey Medical School, Newark, NJ, USA;11. Department of Biochemistry, Sargodha Medical College, Sargodha, Pakistan;12. Institut Necker-Enfants Malades (INEM), Paris, France;13. INSERM, U1151, Paris, France;14. CNRS, UMR8253, Paris, France;15. Departamento de Biología Fundamental, Universidad de Oviedo, Fundación para la Investigación Sanitaria del Principado de Asturias (FINBA), Oviedo, Spain;16. Instituto de Investigación Sanitaria del Principado de Asturias (IISPA), Oviedo, Spain;17. Scientific Computing, LGCR, Sanofi R&D, 94403 Vitry-sur-Seine, France;18. Institute of Molecular Biosciences, NAWI Graz, University of Graz, Humboldtstraße 50, 8010 Graz, Austria;19. BioTechMed-Graz, Humboldtstraße 50, 8010 Graz, Austria;20. Structure Design & Informatics, LGCR, Sanofi R&D, 94403 Vitry-sur-Seine, France;21. Department of Basic Sciences, Faculty of Medicine, University of Crete, Heraklion 70013, Crete, Greece;22. Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France;23. Karolinska Institute, Department of Women’s and Children’s Health, Karolinska University Hospital, Stockholm, Sweden
Abstract:
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  • Keywords:acetylation  aging  autophagy  EP300  longevity  metabolome  salicylate
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