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丁型肝炎病毒感染东方土拔鼠的实验研究
引用本文:金志宏,杨波.丁型肝炎病毒感染东方土拔鼠的实验研究[J].病毒学报,1990,6(1):74-76.
作者姓名:金志宏  杨波
作者单位:河南省医学科学研究所 郑州 (金志宏,杨波,杨小昂,赵国龙,焉晋询,马丽丽,汲振余,陈洪涛,路浩,李艳军,孟林敏),河南省医学科学研究所 郑州(买凯)
摘    要:

关 键 词:丁型肝炎病毒  东方土拔鼠  感染

EXPERIMENTAL STUDIES OF EASTERN WOODCHUCK INFECTED WITH HEPATITIS DELTA VIRUS
Jin Zhihong Yang Bo Yang Xiaoang Zhao Guolong Ye Jinxun Ma Lili Ji Zhenyu Chen Hongtao Lu Hao Li Yanjun Meng Lingmin Mai Kai.EXPERIMENTAL STUDIES OF EASTERN WOODCHUCK INFECTED WITH HEPATITIS DELTA VIRUS[J].Chinese Journal of Virology,1990,6(1):74-76.
Authors:Jin Zhihong Yang Bo Yang Xiaoang Zhao Guolong Ye Jinxun Ma Lili Ji Zhenyu Chen Hongtao Lu Hao Li Yanjun Meng Lingmin Mai Kai
Abstract:An eastern woodchuck chronically infected with WHY was inoculated with one ml of chimpanzee plasma which contained HDV 103CID/ml.WHs-Ag was positive and anti-WHs, HDAg and anti-HD were negative before inoculation. After inoculation, HDAg became positive and its titer was 10 at the fifth week, 1 : 1280 at the eighth week after inoculation. The titer declined later. Degeneration and necrosis of hepatocytes deteriorated gradually and HDAg was detected in hepatocytes after the fifth week.Thirty six nm spherical viral particles were observed under election microscope.
Keywords:Hepatitis D virus Marmota monax Woodchuck hepatitis virus  
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