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短瓣花中的微量新环肽成分
引用本文:程永现,周俊,等.短瓣花中的微量新环肽成分[J].Acta Botanica Sinica,2001,43(7):760-765.
作者姓名:程永现  周俊
作者单位:[1]中国科学院昆明植物研究所植物化学开放实验室,昆明650204 [2]Authorforcorrespondence
摘    要:从中国民间草药短瓣花(Brachystemma calycinum D.Don)干燥根的乙醇提取物中分离得到4个新的微量环八肽,命名为短瓣花环肽A、B、C和D。经光谱分析鉴定。它们的结构分别为cyclo(Pro^1-Phe-Leu-Ala^1-Thr-Pro^2-Ala^2-Gly)(1)、cyclo(Pro^1-Ala-Phe-Trp-Asp-Pro^2-Leu-Gly)(2)、cyclo(Pro^1-Ⅱe-Gly-Pro^2-Val-Ala^1-Ala^2-Tyr)(3)和cyclo(Pro-OMet-Trp-Ⅱe-Gly-Ala-Leu-Asp)(4)。

关 键 词:石竹科  短瓣花  环肽  短瓣花环肽

New Minor Cyclic Peptides from Brachystemma calycinum
Abstract:From the ethanol extract of the roots of Brachystemma calycinum D.Don, a Chinese folk herb, four new minor cyclic peptides namely brachystemin A, B, C and D (1-4) have been isolated. Their structures were established as cyclo (Pro 1_Phe_Leu_Ala 1_Thr_Pro 2_Ala 2_Gly) (1), cyclo (Pro 1_Ala_Phe_Trp_Asp_Pro 2_Leu_Gly) (2), cyclo (Pro 1_Ile_Gly_Pro 2_Val_Ala 1_Ala 2_Tyr) (3) and cyclo (Pro_OMet_Trp_Ile_Gly_Ala_Leu_Asp) (4) respectively by means of extensive spectral methods.
Keywords:Caryophyllaceae  Brachystemma calycinum  cyclic peptide  brachystemin A  B  C  D
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