The quest for the holy "G" of chromosomal passengers |
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Authors: | Burke Daniel J Stukenberg P Todd |
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Affiliation: | Department of Biochemistry and Molecular Genetics, University of Virginia Medical School, Charlottesville, VA 22908, USA. |
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Abstract: | Twelve years after reporting a novel chromosomal passenger protein, Mollinari et al. in this issue of Developmental Cell finally report its molecular identification, and the results are stunning. TD-60 is a member of the RCC1 family of guanine nucleotide exchange factors implicating small GTPases in chromosome congression and cytokinesis. |
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