A low noise multichannel integrated circuit for recording neuronal signals using microelectrode arrays |
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Authors: | Dabrowski W Grybos P Litke A M |
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Affiliation: | Faculty of Physics and Nuclear Techniques, University of Mining and Metallurgy, al. Mickiewicza 30 30059 Krakow, Poland. w.dabrowski@ftj.agh.edu.pl |
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Abstract: | This paper reports on the development of a fully integrated 32-channel integrated circuit (IC) for recording neuronal signals in neurophysiological experiments using microelectrode arrays. The IC consists of 32 channels of low-noise preamplifiers and bandpass filters, and an output analog multiplexer. The continuous-time RC active filters have a typical passband of 20-2000 Hz; the low and the high cut-off frequencies can be separately controlled by external reference currents. This chip provides a satisfactory signal-to-noise ratio for neuronal signals with amplitudes greater than 50 microV. For the nominal passband setting, an equivalent input noise of 3 microV rms has been achieved. A single channel occupies 0.35 mm(2) of silicon area and dissipates 1.7 mW of power. The chip was fabricated in a 0.7 microm CMOS process. |
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