Overcoming obstacles to developing new analgesics |
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| Authors: | Woolf Clifford J |
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| Affiliation: | Neurobiology Center and Program in Neurobiology, Department of Neurology, Children's Hospital Boston, Boston, Massachusetts, USA. clifford.woolf@childrens.harvard.edu |
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| Abstract: | Despite substantial investment by the pharmaceutical industry over several decades, there has been little progress in developing new, efficacious and safe analgesics. As a result, many large pharmaceutical companies are leaving the area of pain medication. Nevertheless, the chances of success could increase if analgesic drug development strategy changed. To achieve such a paradigm shift we must understand why development of drugs for pain relief is so challenging. |
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