Regulation of the ryanodine receptor calcium release channel: a molecular complex system |
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Authors: | Kasai M Kawasaki T Yamaguchi N |
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Affiliation: | Department of Applied Physics, Graduate School of Engineering, Nagoya University, Japan. takahashi@sephia.nuap.nagoya-u.ac.jp |
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Abstract: | The thermal behaviour and structural changes associated with the phase transformation of 1,2-dipalmitoyl-sn-glycerol (DPG) were studied by means of simultaneous X-ray diffraction and differential scanning calorimetry. Metastable DPG solid phases are crystallized from the melted sample by thermal quenching. The metastable phase (alpha-phase) formed initially is converted into a stable phase (beta' phase) at approximately 50 degrees C on heating. It was found that the behaviour of the alpha- to beta'-phase transformation depends on the thermal history. DPG solid samples incubated at approximately 3 degrees C for more than 10 h after cooling transformed directly into the beta'-phase with heat release. On the other hand, in the solid samples without incubation, the alpha-phase once melted and then the crystallization of the beta'-phase occurred successively from the melted state. |
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