(1) Bioinformatics Center, Institute for Chemical Research, Kyoto University, Uji 611-0011, Japan
Abstract:
Background
Many real networks can be understood as two complementary networks with two kind of nodes. This is the case of metabolic networks
where the first network has chemical compounds as nodes and the second one has nodes as reactions. In general, the second
network may be related to the first one by a technique called line graph transformation (i.e., edges in an initial network
are transformed into nodes). Recently, the main topological properties of the metabolic networks have been properly described
by means of a hierarchical model. While the chemical compound network has been classified as hierarchical network, a detailed
study of the chemical reaction network had not been carried out.