Differential expression of WNT4 in testicular and ovarian development in a marsupial |
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| Authors: | Hongshi Yu Andrew J Pask Geoffrey Shaw Marilyn B Renfree |
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| Affiliation: | (1) Department of Zoology, The University of Melbourne, Victoria, 3010, Australia |
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| Abstract: | Background WNT4 is a key regulator of gonadal differentiation in humans and mice, playing a pivotal role in early embryogenesis. Using a marsupial, the tammar wallaby, in which most gonadal differentiation occurs after birth whilst the young is in the pouch, we show by quantitative PCR during early testicular and ovarian development that WNT4 is differentially expressed ingonads. |
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