Prediction of transmembrane helix orientation in polytopic membrane proteins |
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| Authors: | Larisa Adamian Jie Liang |
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| Affiliation: | (1) Department of Bioengineering, University of Illinois at Chicago, M/C 563, 835 S. Wolcott St, Chicago, IL 60612-7340, USA |
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| Abstract: | Background Membrane proteins compose up to 30% of coding sequences within genomes. However, their structure determination is lagging behind compared with soluble proteins due to the experimental difficulties. Therefore, it is important to develop reliable computational methods to predict structures of membrane proteins. |
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