The Almost-one Parameter Hypothesis Applied to Pharmacokinetics of Ethanol Infusion

They say that the pharmacokinetics of constant-rate intravenous infusion of ethanol obeys the Henri-Michaelis-Menten (H-M-M) model. In analysing the original data from the viewpoint of the almost-one parameter hypothesis (see box 1), we found that the whole process should be divided into four phases and the H-M-M model was valid only in the last phase.