拟南芥NPH3/RPT2-Like(NRL)家族蛋白在向光素信号转导通路中的作用研究进展

向光素PHOT1和PHOT2感受蓝光刺激后发生自磷酸化激活,调节植物气孔开放、叶绿体运动、叶片伸展和定位以及向光性(包括根的负向光性和下胚轴的向光性)等多种适应性反应。拟南芥(Arabidopsis thaliana)NRL(NPH3/RPT2-Like)家族成员在向光素介导的信号途径中发挥重要作用,其中NPH3特异调控下胚轴的向光性以及叶片的伸展与定位,RPT2参与调节植物向光性、叶片的伸展与定位以及叶绿体聚光反应等。NCH1是新发现的NRL家族成员,与RPT2以功能冗余的方式调节叶绿体的聚光反应,但不调节避光反应。该文主要综述了NRL蛋白家族成员在向光素介导蓝光信号通路中的作用,并展望了未来的研究方向,旨在为全面揭示NRL家族成员的功能提供线索。

Advances of NPH3/RPT2-Like(NRL)Family Proteins in Phototropin-mediated Signaling in Arabidopsis thaliana

Upon blue light-triggered autophosphorylation,the activated PHOT1 and PHOT2 photoreceptors function solely or redundantly to regulate diverse responses,such as stomatal opening,chloroplast movements,phototropism,and leaf positioning and flattening in Arabidopsis thaliana.Members of NPH3/RPT2-Like family(NRL)are necessary to elicit several photo-responses.NPH3 is required for phototropism,leaf expansion and positioning.RPT2 regulates chloroplast accumulation movement besides NPH3-mediated responses.NCH1 was recently identified as a Phot1-interacting protein that functions redundantly with RPT2 to mediate chloroplast accumulation movement,but not chloroplast avoidance movement.This article summarized the function of NRL family members in phototropin-mediated signaling and prospected further research,thus providing clues for fully revealing the function of the NRL family proteins.