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CYP3A4‐dependent cellular response does not relate to CYP3A4‐catalysed metabolites of C‐1748 and C‐1305 acridine antitumor agents in HepG2 cells
Authors:Ewa Augustin  Magdalena Niemira  Adam Hołownia  Zofia Mazerska
Affiliation:1. Department of Pharmaceutical Technology and Biochemistry, Chemical Faculty, Gdańsk University of Technology, Gdańsk, Poland;2. Department of Clinical Pharmacology, Faculty of Medicine, Medical University of Bia?ystok, Bia?ystok, Poland
Abstract:
Keywords:antitumor acridines  apoptosis  CYP3A4 overexpression  C‐1748 and C‐1305  drug metabolism  HepG2 cells
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