Replicon sizes in non-transformed and SV40-transformed cells, as estimated by a bromodeoxyuridine photolysis method |
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| Authors: | L N Kapp S D Park J E Cleaver |
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| Institution: | Laboratory of Radiobiology, University of California, San Francisco, CA 94143, USA |
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| Abstract: | Replicon sizes were measured in Simian Virus 40 (SV40)-transformed and untransformed normal human, xeroderma pigmentosum (XP), and mouse 3T3 cells with an X-ray plus bromodeoxyuridine (BUdR) photolysis method. Replicon sizes in SV40-transformed cells were at least twice those in untransformed counterparts, but DNA fork displacement rates were only slightly increased. |
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