Gene set enrichment meta-learning analysis: next- generation sequencing versus microarrays |
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Authors: | Gregor Stiglic Mateja Bajgot Peter Kokol |
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Affiliation: | (1) Faculty of Health Sciences, University of Maribor, Zitna ulica 15, 2000 Maribor, Slovenia |
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Abstract: | Background Reproducibility of results can have a significant impact on the acceptance of new technologies in gene expression analysis. With the recent introduction of the so-called next-generation sequencing (NGS) technology and established microarrays, one is able to choose between two completely different platforms for gene expression measurements. This study introduces a novel methodology for gene-ranking stability analysis that is applied to the evaluation of gene-ranking reproducibility on NGS and microarray data. |
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