Concentric-tube airlift bioreactors |
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Authors: | M. Gavrilescu R. Z. Tudose |
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Affiliation: | Chemical Pharmaceutical Research Institute, Research Center for Antibiotics, 6647 - Valea Lupului no. 1, JASSY, Romania, RO
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Abstract: | Mass transfer coefficients were measured in three concentric-tube airlift reactors of different scales (RIMP, V L =0.07 m3;RIS?1,V L =2.50 m3;RIS?2, V L =5.20 m3). The effects of top and bottom clearance and flow resistances at downcorner entrance were studied in water-air system. Experimental results show that h s ,h B and A d /A R ratio affect K L a values as a result of their influence on gas holdup and liquid velocity. The gas-liquid mass-transfer coefficients for all the geometric variables were successfully correlated as Sherwood number with Froude and Galilei numbers, the bottom spatial ratio (B=h B /D R ), the top spatial ratio , the gas separation ratio and the downcomer flow resistance ratio (R=A d /A R ). The proposed empirical model satisfactorily fitted the experimental data obtained in large airlift reactors and some data presented in literature. |
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