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NMR assignments of a hypothetical pseudo-knotted protein HP0242 from Helicobacter pylori
Authors:Chih-Ta Henry Chien  Liang-Wei Wang  Yu-Nan Liu  Ban-Dar Hsu  Ping-Chiang Lyu  Shang-Te Danny Hsu
Institution:1. Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan
2. Department of Chemistry, National Taiwan University, Taipei, Taiwan
3. Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu, Taiwan
4. Institute of Biochemical Science, National Taiwan University, Taipei, Taiwan
Abstract:Many knotted proteins have been discovered recently, but the folding process of which remains elusive. HP0242 is a hypothetical protein from Helicobacter pylori, which is a model system for studying the folding pathway of a knotted protein. In this study, we report the 1H, 13C, and 15N chemical shift assignments of HP0242. The results will enable us to further investigate HP0242 by NMR experiments.
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