Biosynthetic studies with L-[2,3-3H2] valine as precursor of the D-valine moiety in actinomycin. |
| |
| Authors: | K T Mason G J Shaw E Katz |
| |
| Institution: | 1. Department of Microbiology, Georgetown University Schools of Medicine and Dentistry, Washington, D.C. 20007 USA;1. Laboratory of Chemistry, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland 20014 USA |
| |
| Abstract: | The mechanism of inversion of l-valine to its d-enantiomer by Streptomyces parvulus was studied with l-2,3-3H2]valine as precursor. The data favor the view that there is a specific loss of the α-hydrogen of l-valine during the inversion and rule out a reaction mechanism in which α,β-dehydrovaline (valinyl) participates as an intermediate. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
