Evolutionary proteomics identifies amino acids essential for ligand-binding of the cytokinin receptor CHASE domain |
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| Authors: | Alexander Heyl Klaas Wulfetange Birgit Pils Nicola Nielsen Georgy A Romanov Thomas Schmülling |
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| Institution: | 1.Institute of Biology/Applied Genetics,Free University of Berlin,Berlin,Germany;2.Department of Bioinformatics, Biocenter,Julius Maximilian University,Würzburg,Germany;3.Institute of Plant Physiology,Russian Academy of Sciences,Moscow,Russia |
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| Abstract: | Background In plants the hormone cytokinin is perceived by members of a small cytokinin receptor family, which are hybrid sensor histidine
kinases. While the immediate downstream signaling pathway is well characterized, the domain of the receptor responsible for
ligand binding and which residues are involved in this process has not been determined experimentally. |
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