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A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates
Authors:Zachary A. Bornholdt  Andrew S. Herbert  Chad E. Mire  Shihua He  Robert W. Cross  Anna Z. Wec  Dafna M. Abelson  Joan B. Geisbert  Rebekah M. James  Md Niaz Rahim  Wenjun Zhu  Viktoriya Borisevich  Logan Banadyga  Bronwyn M. Gunn  Krystle N. Agans  Ariel S. Wirchnianski  Eileen Goodwin  Kevin Tierney  John M. Dye
Affiliation:1. Mapp Biopharmaceutical, Inc., San Diego, CA, USA;2. United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD, USA;3. Department of Microbiology and Immunology, Galveston National Laboratory, University of Texas Medical Branch at Galveston, Galveston, TX, USA;4. Special Pathogens Program, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, MB, Canada;5. Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, USA;6. The Ragon Institute, Cambridge, MA, USA;7. Department of Medical Microbiology, University of Manitoba, Winnipeg, MB, Canada;8. Adimab LLC, Lebanon, NH, USA
Abstract:
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  • Keywords:ebolavirus  EBOV  SUDV  BDBV  Sudan  Bundibugyo  pan-ebolavirus  MBP134  ADI-15878  ADI-23774
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