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Methicillin resistant Staphylococcus aureus adhesion to human umbilical vein endothelial cells demonstrates wall shear stress dependent behaviour
Authors:Kayla D Viegas,Sharul S Dol,M Mehdi Salek,Robert D Shepherd,Robert M Martinuzzi,Kristina D Rinker
Affiliation:(1) Department of Mechanical Engineering, Schulich School of Engineering, University of Calgary, Calgary, AB, Canada;(2) Department of Chemical and Petroleum Engineering, Schulich School of Engineering, University of Calgary, Calgary, AB, Canada;(3) Centre for Bioengineering Research and Education, Schulich School of Engineering, University of Calgary, Calgary, AB, Canada;(4) Department of Physiology and Pharmacology, Faculty of Medicine, University of Calgary, Calgary, AB, Canada;(5) Calvin, Phoebe and Joan Snyder Institute of Infection, Immunity and Inflammation, Faculty of Medicine, University of Calgary, Calgary, AB, Canada
Abstract:

Background  

Methicillin-resistant Staphylococcus aureus (MRSA) is an increasingly prevalent pathogen capable of causing severe vascular infections. The goal of this work was to investigate the role of shear stress in early adhesion events.
Keywords:
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