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Sperm DNA fragmentation and oxidation are independent of malondialdheyde |
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| Authors: | Nassira Zribi Nozha Feki Chakroun Henda Elleuch Fatma Ben Abdallah Afifa Sellami Ben Hamida Jalel Gargouri Faiza Fakhfakh Leila Ammar Keskes |
| Institution: | (1) Laboratory of Human Molecular Genetics, Sfax Faculty of Medicine, Avenue Magida Boulila, 3028 Sfax, Tunisia;(2) Laboratory of Histology-Embryology, Sfax Faculty of Medicine, Avenue Magida Boulila, 3028 Sfax, Tunisia;(3) Regional Center of Blood Transfusion of Sfax, El Ain Road, 3029 Sfax, Tunisia |
| Abstract: | BackgroundThere is clinical evidence to show that sperm DNA damage could be a marker of sperm quality and extensive data exist on the relationship between DNA damage and male fertility status. Detecting such damage in sperm could provide new elements besides semen parameters in diagnosing male infertility. We aimed to assess sperm DNA fragmentation and oxidation and to study the association between these two markers, routine semen parameters and malondialdehyde formation. |
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