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Polypeptide models of collagen. Solution properties of (Gly-Pro-Sar)n and (Gly-Sar-Pro)n. |
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| Authors: | V S Ananthanarayanan S K Brahmachari R S Rapaka R S Bhatnagar |
| Abstract: | Our studies on the solution conformation of (Gly-Pro-Sar)n and (Gly-Sar-Pro)n synthesized as polypeptide models for collagen are reported. It is found that, while (Gly-Pro-Sar)n exists in ordered triple-helical conformation, (Gly-Sar-Pro)n remains as a disordered random coil in water. Addition of certain helix-promoting solvents seems to generate order in (Gly-Sar-Pro)n. |
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