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Age‐associated reduction of cellular spreading/mechanical force up‐regulates matrix metalloproteinase‐1 expression and collagen fibril fragmentation via c‐Jun/AP‐1 in human dermal fibroblasts |
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| Authors: | Zhaoping Qin John J Voorhees Gary J Fisher Taihao Quan |
| Institution: | Department of Dermatology, University of Michigan Medical School, , Ann Arbor, Michigan, USA |
| Abstract: | |
| Keywords: | aging c‐Jun/AP‐1 extracellular matrix microenvironment fibroblast mechanical force MMP‐1 |