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Acremonium strictum: Report of a Rare Emerging Agent of Cutaneous Hyalohyphomycosis with Review of Literatures
Authors:Ajanta Sharma  N. K. Hazarika  Purnima Barua  M R Shivaprakash  Arunaloke Chakrabarti
Affiliation:1. Department of Microbiology, Gauhati Medical College, Guwahati, 781032, Assam, India
2. Department of Microbiology, Jorhat Medical College, Jorhat, 785001, Assam, India
3. Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India
Abstract:We present a case of cutaneous hyalohyphomycosis due to Acremonium strictum in an immunocompetent individual along with an overview of fungal infections caused by A. strictum. The diagnosis was confirmed by the presence of hyphae in microscopic examination of cutaneous biopsy and discharge, positive culture for A. strictum and sequencing of the isolate at reference centre. The infection resolved with itraconazole and terbinafine. Cutaneous or subcutaneous infections of A. strictum have rarely been reported. Fungemia or disseminated infection often with fatal outcome in immunocompromised patients was the most common presentation of A. strictum infection found in the literatures. The studies also reveal worldwide variation in the treatment regime and outcome of the treatment.
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