Foxn4--a new member of the forkhead gene family is expressed in the retina |
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| Authors: | Gouge A Holt J Hardy A P Sowden J C Smith H K |
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| Affiliation: | The Galton Laboratory, Department of Biology, University College London, 4 Stephenson Way, London NW1 2HE, UK. |
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| Abstract: | We report the cloning and expression of a novel murine forkhead/winged helix family member--Foxn4--that is expressed during neural development in the retina, the ventral hindbrain and spinal cord and dorsal midbrain. Retinal Foxn4 expression is associated with the zone of proliferating progenitor cells. In the mouse mutant ocular retardation (or(J)), Foxn4 expression in the retina is significantly reduced and terminates prematurely. |
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