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Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model |
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| Authors: | Alvaro Ruiz-Martinez Chang Gong Hanwen Wang Richard J Sov Haoyang Mi Holly Kimko Aleksander S Popel |
| Institution: | 1. Department of Biomedical Engineering, Johns Hopkins, University School of Medicine, Baltimore, Maryland, United States of America;2. Clinical Pharmacology & Quantitative Pharmacology, AstraZeneca, Gaithersburg, Maryland, United States of America;3. Department of Oncology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America; H. Lee Moffitt Cancer Center & Research Institute, UNITED STATES |
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