| MicroRNA与神经系统重大疾病 |
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| 引用本文： | 汪进业,蔡荣,罗本燕.MicroRNA与神经系统重大疾病[J].生物化学与生物物理进展,2009,36(1):25-32. |
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| 作者姓名： | 汪进业 蔡荣 罗本燕 |
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| 作者单位： | 1. 浙江大学医学院附属第一医院神经内科,杭州,310003
2. 浙江理工大学生命科学学院,杭州,310018 |
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| 基金项目： | 浙江省自然科学基金(Y2080132), 浙江省科技支撑和引导计划(2007C33007)和国家自然科学基金(30570582)资助项目. |
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| 摘 要： | 目前有研究证实microRNA参与了神经系统生长发育和生理功能的调控，它也与可塑性障碍性疾病、神经系统退行性疾病、神经系统肿瘤、脑血管疾病等重大疾病的发生发展相关．随着microRNA研究领域的发展，一些重大神经系统疾病的相关发病机制将有可能被阐释．
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| 关 键 词： | 神经系统生长发育 神经系统重大疾病 |
| 收稿时间： | 6/3/2008 12:00:00 AM |
| 修稿时间： | 2008/9/13 0:00:00 |
Functions of MicroRNA in Nervous System Regulation |
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| WANG Jin-Ye,CAI Rong and LUO Ben-Yan.Functions of MicroRNA in Nervous System Regulation[J].Progress In Biochemistry and Biophysics,2009,36(1):25-32. |
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| Authors: | WANG Jin-Ye CAI Rong and LUO Ben-Yan |
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| Institution: | Department of Neurology First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China;College of Life Science, Zhejiang Sci-Tech University, Hangzhou 310018, China;Department of Neurology First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China |
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| Abstract: | Many investigations have demonstrated that microRNA (miRNA) is not only involved in the modulation of nerve cell growth and physiological activity, but also responsible for dysfunctions in synaptogenesis or synaptic plasticity, neurodegenerative diseases, tumorgenesis in the nervous system, as well as in cerebrovascular disorders. With the intensive researches in miRNA, it is possible gradually to explain the related pathogenic mechanisms of some major diseases in the nervous system. |
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| Keywords: | microRNA |
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