Stimulation of steroid glucuronidation by uridine diphosphate N-acetylglucosamine and by microsomal disruption. |
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Authors: | J Wilkinson and T Hallinan |
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Abstract: | Glucuronidation of oestrone and of oestradiol in microsomal fractions was markedly and significantly stimulated by UDP-N-acetylglucosamine and by ultrasonication: Triton X-100 also stimulated. This is consistent with compartmentation of UDP-glucuronyl-transferase. Stimulation by UDP-N-acetylglucosamine may be physiologically significant. |
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