Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system |
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Authors: | John J Hutton Anil G Jegga Sue Kong Ashima Gupta Catherine Ebert Sarah Williams Jonathan D Katz Bruce J Aronow |
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Affiliation: | (1) Department of Pediatrics and Biomedical Informatics, University of Cincinnati and Cincinnati Children's Hospital Research Foundation, 45229 Cincinnati, Ohio, USA |
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Abstract: | Background In this study we have built and mined a gene expression database composed of 65 diverse mouse tissues for genes preferentially expressed in immune tissues and cell types. Using expression pattern criteria, we identified 360 genes with preferential expression in thymus, spleen, peripheral blood mononuclear cells, lymph nodes (unstimulated or stimulated), orin vitroactivated T-cells. |
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