| 眼镜蛇毒对成年大鼠海马CA3区Nestin表达的影响 |
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| 引用本文： | 马同军,丁见,刘嵩,熊克仁. 眼镜蛇毒对成年大鼠海马CA3区Nestin表达的影响[J]. 蛇志, 2012, 24(2): 93-95 |
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| 作者姓名： | 马同军 丁见 刘嵩 熊克仁 |
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| 作者单位： | 皖南医学院解剖学教研室,安徽芜湖,241002 |
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| 基金项目： | 安徽省高等学校省级自然科学研究项目(项目编号:KJ2009B292Z) |
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| 摘 要： | 目的探讨眼镜蛇毒对成年大鼠海马CA3区巢蛋白(Nestin)阳性细胞表达的影响。方法采用免疫组织化学方法,观察并比较Nestin阳性细胞在眼镜蛇毒组、生理盐水组、正常对照组大鼠海马CA3区的表达。结果眼镜蛇毒组大鼠海马CA3区Nestin阳性细胞较生理盐水组、正常对照组表达明显增强(P0.01)。结论眼镜蛇毒对成年大鼠海马CA3区Nestin表达有上调作用。
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| 关 键 词： | 眼镜蛇毒 海马CA3区 Nestin 大鼠 |
Effect of Naja naja atra venom on the expression of Nestin in hippocampus CA3 region of adult rats |
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| MA Tong-jun , DING Jian , LIU Song , XIONG Ke-ren. Effect of Naja naja atra venom on the expression of Nestin in hippocampus CA3 region of adult rats[J]. Journal of Snake, 2012, 24(2): 93-95 |
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| Authors: | MA Tong-jun DING Jian LIU Song XIONG Ke-ren |
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| Affiliation: | (Department of Anatomy,Wannan Medical College,Wuhu,Anhui,241002,China) |
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| Abstract: | Objective To investigate the effects of Naja naja atra venom on the expression of Nestin in hippocampus CA3 region of adult rats.Methods The methods of immunohistochemistry technique were used to observe the different expression of Nestin positive cells in Naja naja atra venom group,saline group and control group.Results The number of Nestin positive cells in hippocampus CA3 region of Naja naja atra venom group were higher markedly than that of saline and control groups(P<0.01).Conclusion Naja naja atra venom could increase the expression of Nestin in hippocampus CA3 region of adult rats. |
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| Keywords: | Naja naja atra venom Hippocampus CA3 region Nestin Rat |
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