Polarized diffuse reflectance measurements on cancerous and noncancerous tissues |
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Authors: | Sandeep Manhas Mahesh K. Swami Hari S. Patel Abha Uppal Nirmalya Ghosh Pradeep K. Gupta |
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Affiliation: | Laser Biomedical Applications and Instrumentation Division, R & D Block‐D, Raja Ramanna Centre for Advanced Technology, Indore – 452013, India |
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Abstract: | We report the measurement of polarization parameters (linear retardance, diattenuation and depolarization) of normal and malignant tissue from human oral cavity and breast over the spectral range 390 nm to 550 nm. These parameters were determined using the 3 × 3 Mueller matrix, the elements of which could be determined using linear polarization measurements only. The significant differences observed in the polarization parameters of the normal and malignant tissues appear to arise because of the changes in the collagen matrix in the two tissue types. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim) |
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Keywords: | Tissue polarimetry depolarization diffuse reflectance optical diagnosis |
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