Real‐time in vivo imaging of adult Zebrafish brain using optical coherence tomography |
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| Authors: | K. Divakar Rao Aneesh Alex Yogesh Verma Sreeja Thampi Pradeep K. Gupta |
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| Affiliation: | 1. Laser Biomedical Applications & Instrumentation Division, Raja Ramanna Centre for Advanced Technology, Indore – 452 013, India;2. Presently with the School of Optometry and Vision Sciences, Cardiff University, Cardiff, UK;3. Presently with the School of Information and Mechatronics, Gwangju Institute of Science and Technology, Gwangju, Republic of Korea |
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| Abstract: | We report noninvasive imaging of the brain of adult Zebrafish (Danio rerio) using real time optical coherence tomography (OCT) capable of acquiring cross sectional 2D OCT images @ 8 frames/sec. Anatomic features such as telencephalon, tectum opticum, eminentia Granularis and cerebellum were clearly resolved in the OCT images. A 3D model of Zebrafish brain was reconstructed, for the first time to our knowledge, using these 2D OCT images. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim) |
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| Keywords: | Optical coherence tomography Zebrafish 3‐D imaging |
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