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Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression |
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| Authors: | Masaru Mitsui Makiya Nishikawa Lei Zang Mitsuru Ando Kayoko Hattori Yuki Takahashi Yoshihiko Watanabe Yoshinobu Takakura |
| Institution: | 1. Department of Biopharmaceutics and Drug Metabolism, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan;2. Department of Molecular Microbiology, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan |
| Abstract: | |
| Keywords: | cancer gene therapy CpG motif hydrodynamic injection interferon‐γ methylation pro‐inflammatory cytokine |