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A loop in the N‐lobe of human serum transferrin is critical for binding to the transferrin receptor as revealed by mutagenesis,isothermal titration calorimetry,and epitope mapping |
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| Authors: | Anne B. Mason Shaina L. Byrne Stephen J. Everse Samantha E. Roberts N. Dennis Chasteen Valerie C. Smith Ross T. A. MacGillivray Banu Kandemir Fadi Bou‐Abdallah |
| Affiliation: | 1. Department of Biochemistry, College of Medicine, University of Vermont, 89 Beaumont Avenue, Burlington, VT 05405, USA;2. Department of Chemistry, University of New Hampshire, Parsons Hall, Durham, NH 03824, USA;3. Department of Biochemistry and Molecular Biology and Centre for Blood Research, University of British Columbia, Vancouver, BC V6T 1Z3, Canada;4. Department of Chemistry, State University of New York at Potsdam, Stowell Hall, Potsdam, NY 13676, USA |
| Abstract: | |
| Keywords: | human serum transferrin isothermal titration calorimetry binding isotherms transferrin receptor epitope recombinant protein BHK cells His‐tag |